Jan has expertise in organic chemistry and has been participating in numerous projects involving synthesis of fytoestrogens, juvenile hormons as well as the chemistry of calixarenes, carboranes and derivatization of nanodiamonds. For the last 10 years he has been mainly focusing on medicinal chemistry and especially on novel mitochondrially targeted substances with promising biological activity. He is one of the inventors of the substance MitoTam, which is undergoing Phase I clinical trial involving oncological patients. He works as a scientist in the Service technology laboratory (STL) at Institute of Biotechnology Czech Academy of Sciences. STL design and synthetize not only mitochondrially targeted substances but also offers a custom synthesis or academic collaborations. Jan is also involved in advanced technology transfer including design, documentation and management of preclinical and clinical trials.