Preventive Oncology 2020 is very much delighted, to have organized this enthusiastic conference and hopes for a fruitful event to be well received by speakers, sponsors, exhibitors and attendees. With the ever-growing incidence of cancer, causing millions of deaths each year, preventive oncology conference hopes this congruence of experts from all over the globe is the need of the hour.
The conference series, hopes to provide platform for workshops and hands-on training apart from the regular oral and poster presentation, hoping to attract the younger crowd- the students who are the future whose participation in preventing cancer is highly important. The Young Researchers forum provides the student community, young researchers, junior research fellows, PhD aspirants a wonderful opportunity to present and participate at the conference at much cheaper price. There is also Young Researcher award, presented to the best attendee from the category. Apart from that, best poster award is another spotlight to look forward to.
With all said, the World Congress on Preventive oncology hopes to unite everyone in the field of oncology from all over the world to imply the importance on prevention of cancer, as it is always easier than the cure.
01. Preventive Oncology:
Preventive oncology is any measure that is taken to prevent development or progression of malignant process. Around one third of cancer deaths are due to the five leading behavioral and dietary risks: high body mass index, low fruit and vegetable intake, lack of physical activity, tobacco use, alcohol use, and one half of all cancer cases either arise from modifiable risk factors or can be detected as precursor lesions before the development of disease with metastatic potential.
Prevention of cancer can take place on several different levels: primary prevention addresses the cause of cancer so disease does not occur, secondary prevention identifies disease before the onset of symptoms and keeps it from becoming more extensive, and tertiary prevention reduces complications and progression of disease once it has become clinically apparent.
Gene therapy may help prevent cancer metastasis
Blood sample new way of detecting cancer
Breakthrough: Using skin cells to kill cancer
T-Cell Therapy gives hope for advanced lymphoma
02. Molecular Oncology:
Molecular Oncology refers to the investigation of the chemistry of cancer and tumors at the molecular scale. The examinations are at the science of malignancy and tumors at the sub-atomic scale. Additionally the advancement and use of molecularly focused on treatments. In atomic oncology the distinguish qualities are included in the improvement of disease.
Pre malignant lesions
Integrating tumor microenvironment
Tumor cells metabolize glucose, lactate, pyruvate, hydroxybutyrate, acetate, glutamine and fatty acids at much higher rates than their non-tumor equivalents; however, the metabolic ecology of tumors is composite because they contain multiple metabolic compartments, which are linked by the transfer of these catabolites. This metabolic changeability and flexibility enables tumor cells to generate ATP as an energy source, while maintaining the reduction–oxidation (redox) balance and committing resources to biosynthesis processes that are essential for cell survival, growth and proliferation.
Preclinical and clinical studies of metabolism-related cancer therapies
Oral cavity cancers the tumor is growing into an area called the masticator space and Oropharyngeal cancers the tumor is growing into a muscle called the lateral pterygoid muscle. And the tumor is growing into the nasopharynx (the area of the throat that is behind the nose).
Indirect pharyngoscopy and laryngoscopy diagnostic procedures
Direct (flexible) pharyngoscopy and laryngoscopy
05. Anti-Cancer Drugs:
Anticancer drugs are used to control the growth of cancerous cells. Cancer is commonly defined as the uncontrolled growth of cells, with loss of differentiation and commonly, with metastasis, spread of the cancer to other tissues and organs. Anticancer medications are utilized when the tumor has spread, or may spread, to all regions of the body.
Nanotechnology in cancer drugs
Cancer immune prevention is the prevention of cancer onset with immunological means such as vaccines, Immuno-stimulators or antibodies. Most tumor-associated antigens (TAA) are self-molecules that are abnormally expressed in cancer cells and become targets of antitumor immune responses. Antibodies and T cells specific for some TAAs have been found in healthy individuals and are associated with lowered lifetime risk for developing cancer. Lower risk for cancer has also been associated with a history of febrile viral diseases. A CIP study identified new antibodies against tumor cell proteins that were elicited by influenza infection. Cancer vaccines based on human tumor-associated antigens (TAA) have been tested in patients with advanced or recurrent cancer, in combination with or following standard therapy.
Immuno Prevention of Tumors Caused by Viruses
Immuno Prevention of non-infectious tumor
Cancer Immune Editing
07. Cancer Epidemiology:
Cancer epidemiology is the study of the distribution and determinants of the likelihood of cancer development. Cancer epidemiology can be used to identify events that increase or decrease cancer occurrence in specific people cancer epidemiology uses epidemiological methods to find the cause of cancer and to identify and develop improved treatments. Normally Squamous cell carcinoma of the lung is a central rather than a peripheral form of lung cancer. Rates of squamous cell carcinoma in the lung periphery are typically sited in the 15-30% range. Given the differences in cell biology and carcinogenesis of central versus peripheral SCC, a potential epidemiologic shift might suggest a change in tumor biology.
Squamous cell carcinoma epidemiology
08. Gynecologic Oncology:
A Gynecologic oncology is study of which specializes in the diagnosis and treatment of women with cancer of the reproductive organs Including ovarian cancer, uterine cancer, vaginal cancer, cervical cancer, and vulvar cancer. The primary treatment for ovarian cancer, followed in most patients by systemic chemotherapy. By the Aggressive exploitation of operative laparoscopy, even only for selected patients, into the surgical practice of a gynecologic oncology service demonstrates significant improvements in LOS (laparoscopy on length of stay) without adversely affecting surgical complication rates based on different types of cancers.
Gestational trophoblastic disease
Ovarian cancer- including fallopian tube, peritoneal, germ cell, and stromal cell
09. Hematologic Oncology:
A hematologic-oncology is the study that involves in the diagnosis, treatment and/or prevention of blood diseases and cancers such as iron-deficiency anemia, hemophilia, sickle-cell disease, leukemia and lymphoma. This physician is trained in hematology — the study of blood — and oncology — the study of cancer. Hematologist-oncologists do not usually treat operable cancers such as prostate cancer, but specialize in treating blood cancers, such as Hodgkins and non-Hodgkins lymphomas, leukemias and multiple myelomas. A hematologist-oncologist may also specialize in the management of solid tumors.
Hematologists also conduct studies in oncology and work with oncologists, people who may specialize only in that field instead of both-the medical treatment of cancer. There are various disorders that people are affected by hematology. A few of these different types of blood conditions that are looked at include anemia, hemophilia, general blood clots, bleeding disorders, etc. As for related blood cancers such as leukemia, myeloma, and lymphoma, these are more serious cases that need to be diagnosed
10. Stem Cells Therapy:
Stem-cell therapy is the use of stem cells to treat or prevent a disease or condition. In a typical stem cell transplant for cancer very high doses of chemo are used, sometimes along with radiation therapy, to try to kill all the cancer cells. This treatment also kills the stem cells in the bone marrow. Soon after treatment, stem cells are given to replace those that were destroyed. These stem cells are given into a vein, much like a blood transfusion. Over time they settle in the bone marrow and begin to grow and make healthy blood cells. This process is called engraftment.
Autologous stem cell transplants
Allogeneic stem cell transplants
Syngeneic stem cell transplants
Surgery is the removal of the tumor and surrounding tissue during an operation. A doctor who specializes in treating cancer using surgery is called a surgical oncologist. Surgery is the oldest type of cancer therapy and remains an effective treatment for many types of cancer today. For most types of cancer, a biopsy is the only way to make a definitive diagnosis. During a surgical biopsy, the surgeon makes a cut called an incision in the skin. Then, he or she removes some or all of the suspicious tissue. Tumor removal, also called curative or primary surgery. Surgery is most commonly used to remove the tumor and some of the surrounding healthy tissue. The tissue surrounding the tumor is called the margin.
Lung cancer surgery
12. Cancer Cell Biology:
The cell is the fundamental unit of life. It is the smallest structure of the body capable of performing all of the processes that define life. Each of the organs in the body, such as the lung, breast, colon, and brain, consists of specialized cells that carry out the organ's functions such as the transportation of oxygen, digestion of nutrients, excretion of waste materials, locomotion, reproduction, thinking, etc. here are two general sorts of quality transformations. One write, prevailing change, is brought about by a variation from the norm in one quality in a couple. The second broad kind of transformation, latent change, is described by both qualities in the pair being harmed.
Nanotechnology in Cancer
13. Radiation Oncology:
Radiation therapy occurs in the presence of biochemical recurrence after prostatectomy to assess whether this results in shifts of Histo-pathological prognostic factors such as the Gleason Score by using ionizing radiation (such as mega-voltage X-rays or radionuclides) in the treatment of cancer. The field of radiation oncology covers the integration of radiation therapy into multimodal treatment approaches. Radiation Oncology provides an open access forum for researchers and clinicians involved in the management and treatment of cancer patients, bringing together the latest research and advances in the field. Advances in treatment technology, as well as improved understanding of the underlying biological resistance mechanisms, will further strengthen the role of radiation oncology.
Stereotactic body radiation therapy (SBRT)
Intensity Modulated Radiotherapy (IMRT)
Prostate Seed Implant
It is provides for bits of learning on the etiology, change, and potential treatment of various ailments through reproducing cell instruments. Cell reconstructing is the way toward guiding full grown cells to a primitive condition of quality expression. The etiology and pathogenesis of SLE have not been completely seen. Innate, biological and viral maladies and diverse components might be related to the pathogenetic parts of Systemic lupus erythematosus. Interleukin-2 (IL-2) is a fundamental cytokine conveyed by T cells upon order and is basic for the time of T authoritative cells and incitation induced cell destruction. In SLE patients, T cells indicate reduced capacity to convey IL-2. Handicapped IL-2 expression realized lessened period of authoritative T lymphocytes, and deformation of activation affected cell passing.
· Physiological cellular reprogramming
Treating menopausal symptoms with estrogen and progestin together is known as estrogen-progestin therapy or combined hormone therapy. Hormonal replacement therapy (HRT) has a higher risk of being diagnosed with breast cancer. Before the link between HRT use and breast cancer risk was established, many postmenopausal women took HRT for many years to ease menopausal symptoms (hot flashes, fatigue) and to reduce bone loss. Since 2002, when research linked HRT and risk, the number of women taking HRT has dropped dramatically. Still, many women continue to use HRT to handle bothersome menopausal symptoms.
postmenopausal hormone therapy
Estrogen replacement therapy
Menopausal hormone therapy
Cyclic hormone therapy
16. Clinical Oncology:
Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer. The three components which have improved survival in cancer are Prevention -This is by reduction of risk factors like tobacco and alcohol consumption. Treatment - Multi-modality management by discussion in tumor board and treatment in a comprehensive cancer center.
diagnosis and staging
Surgery is not considered an appropriate cancer prevention option for women who are not at the highest risk of breast cancer. There have been many recent advances in cancer prevention, including improved understanding of cancer biology, better characterization of pre-malignant disease, significant advances in cancer surveillance, and identification of effective chemo-prevention regimens. The issues governing decision making for surgical prevention vary widely among different cancer types, and include consideration of the age and level of cancer risk of the individual, the effectiveness of cancer surveillance for the particular organ at risk, the aggressiveness of the cancer once present, and the morbidity of surgery.
Prolonged thrombo prophylaxis
Esophageal cancer surgery
18. Immuno Oncology:
Immuno-oncology therapies are medicines that use the body’s immune system to fight cancer. Immuno-oncology therapies activate our immune system, making it able to recognize cancer cells and destroy them Immune oncology refers to immune system. It is a collection of organs, cells and special molecules that helps protect you from infections, cancer and other diseases. When a different (foreign) organism enters into the body, for example a bacterium, the immune system recognizes it and then attacks it, preventing it from causing harm. This process is called an immune response. Immuno-oncology therapies were found that provide lasting anti-cancer benefits to patients who previously had very few treatment options available to them. Several immuno-oncology therapies are in the process of being approved for use by patients in Europe, for the treatment of advanced melanoma, lung cancer, colorectal, renal, prostate cancer and many other cancers.
Cell and gene therapy
It is another interdisciplinary region including organic, measurable and computational sciences. Now a day’s bioinformatics innovation is for the most part utilized for the special growth investigation. Ribosomal S6 protein kinase 4 (RSK4) is a vital novel tumor silencer that hinders bosom disease cell development and initiates senescence. Utilizing pair proclivity cleaning, we got protein buildings that associated with RSK4 or RSK4m. Mass range examination was performed to distinguish the acquired protein edifices, and bioinformatics investigation was performed.
20. Oncology Nursing:
An oncology nurse is a nursing professional who specializes in caring for people with cancer. Oncology nurses often serve as your first line of communication, and help coordinate the many aspects of your care throughout cancer treatment.
Oncology nursing practice
Oncology nursing and cancer care
Oncology nursing in USA
Researchers are growing new treatments that objective specific sorts of tumor cells and limit their development. All alone or in blend with other option medications, these treatments can diminish the extent of tumors and manifestations. Some imaginative treatments give seek after individuals with malignancies that have been impervious to more medicines.
Role of Nano technology in cancer
Standard training on disease anticipation
22. Cancer Genetics:
Cancer is a genetic disease that is, cancer is caused by certain changes to genes that control the way our cells function, especially how they grow and divide. These changes include mutations in the DNA that makes up our genes Genetic changes that increase cancer risk can be inherited from our parents if the changes are present in germ cells, which are the reproductive cells of the body (eggs and sperm). In general, cancer cells have more genetic changes than normal cells. But each person’s cancer has a unique combination of genetic alterations. Some of these changes may be the result of cancer, rather than the cause. As the cancer continues to grow, additional changes will occur. Even within the same tumor, cancer cells may have different genetic changes.
1. Clinical DNA sequencing
2. Genetic testing on hereditary
3. Childhood cancer genomics
5. Genetics of cancer
Obstetrics and Gynecology is the medical specialty that deals with obstetrics and gynaecology. The postgraduate training program for both aspects is unified. This combined training prepares the practicing OB/GYN to be adept at the care of female reproductive organs' health and at the management of pregnancy.
Gynecology is the specialized field of medicine dealing with the health of a woman's genital system. The genital system consists of the reproductive organs, including the uterus (the womb; the organ in which a fetus develops), cervix (the opening between the uterus and the vagina), ovaries (organs that produce eggs and sex hormones), fallopian tubes (organs that carry eggs from the ovaries to the uterus), vagina (the muscular tube that extends from the uterus to outside the body), as well as their supporting structures.
Obstetrics is the field of study concentrated on pregnancy, childbirth, and the postpartum period. As a medical specialty, obstetrics is combined with gynaecology under the discipline known as obstetrics and gynaecology.
Midwifery encompasses care of women during pregnancy, labour, and the postpartum period, as well as care of the new-born and the one who is a health science and health profession that deals with pregnancy, childbirth, and the postpartum period. It includes measures aimed at preventing health problems in pregnancy, the detection of abnormal conditions, the procurement of medical assistance when necessary, and the execution of emergency measures in the absence of medical help.
Midwifery, as known as obstetrics, is a health science and health profession that deals with pregnancy, childbirth, and the postpartum period (including care of the newborn), besides sexual and reproductive health of women throughout their lives. In many countries, midwifery is a medical profession (special for its independent and direct specialized education; should not be confused with a medical specialty, which depends on a previous general training).A professional in midwifery is known as a midwife.
25. Thyroid problems
Thyroid disorders are conditions that affect the thyroid gland, a butterfly-shaped gland in the front of the neck. The thyroid has important roles to regulate numerous metabolic processes throughout the body. Different types of thyroid disorders affect either its structure or function. The thyroid gland is located below the Adam's apple wrapped around the trachea (windpipe). A thin area of tissue in the gland's middle, known as the isthmus, joins the two thyroid lobes on each side. The thyroid uses iodine to produce vital hormones. Thyroxine, also known as T4, is the primary hormone produced by the gland. After delivery via the bloodstream to the body's tissues, a small portion of the T4 released from the gland is converted to triiodothyronine (T3), which is the most active hormone. The function of the thyroid gland is regulated by a feedback mechanism involving the brain.
26. Family Planning
Family planning is sometimes used as a synonym or euphemism for access to and the use of contraception. However, it often involves methods and practices in addition to contraception. Family planning is the practice of controlling the number of children in a family and the intervals between their births, particularly by means of artificial contraception or voluntary sterilization. Because "family" is included in the concept's name, consideration of a couple's desire to bear children, in the context of a family unit, is often considered primarily. Contemporary notions of family planning, however, tend to place a woman and her childbearing decisions at the center of the discussion, as notions of women's empowerment and reproductive autonomy have gained traction in many parts of the world. Family planning may involve consideration of the number of children a woman wishes to have, including the choice to have no children, as well as the age at which she wishes to have them. These matters are obviously influenced by external factors such as marital situation, career considerations, financial position, and any disabilities that may affect their ability to have children and raise them, besides many other considerations. If sexually active, family planning may involve the use of contraception and other techniques to control the timing of reproduction.
Infertility is the inability of a person, animal or plant to reproduce by natural means. It is usually not the natural state of a healthy adult organism, except notably among certain eusocial species. In humans, infertility may describe a woman who is unable to conceive as well as being unable to carry a pregnancy to full term. There are many biological and other causes of infertility, including some that medical intervention can treat. It refers to an inability to conceive after having regular unprotected sex. Infertility can also refer to the biological inability of an individual to contribute to conception, or to a female who cannot carry a pregnancy to full term. In many countries infertility refers to a couple that has failed to conceive after 12 months of regular sexual intercourse without the use of contraception.
Abortion, basically of two types: induced and spontaneous, is the ending of pregnancy by removing a fetus or embryo before it can survive outside the uterus. An abortion that occurs spontaneously is also known as a miscarriage. An abortion may be caused purposely and is then called an induced abortion, or less frequently, "induced miscarriage". The word abortion is often used to mean only induced abortions. A similar procedure after the fetus could potentially survive outside the womb is known as a "late termination of pregnancy".
Birth control, also known as contraception and fertility control or preservation, is a method or device used to prevent pregnancy. Birth control has been used since ancient times, but effective and safe methods of birth control only became available in the 20th century. Planning, making available and using birth control is called family planning. Some cultures limit or discourage access to birth control because they consider it to be morally, religiously, or politically undesirable. The most effective methods of birth control are sterilization by means of vasectomy in males and tubal ligation in females, intrauterine devices (IUDs), and implantable birth control.
In vitro fertilization (or fertilization; IVF) is a type of assisted reproductive technology used for infertility treatment and gestational surrogacy in cases like: Blocked or damaged fallopian tubes; Male factor infertility including decreased sperm count or sperm motility. It is a process by which an egg is fertilized by sperm outside the body: in vitro ("in glass"). The process involves monitoring and stimulating a woman's ovulatory process, removing an ovum or ova (egg or eggs) from the woman's ovaries and letting sperm fertilize them in a liquid in a laboratory. The fertilised egg (zygote) is cultured for 2–6 days in a growth medium and is then transferred to the same or another woman's uterus, with the intention of establishing a successful pregnancy.
Ovulation is the point at which a develop egg is discharged from the ovary, pushed down the fallopian tube, and is made accessible to be treated. Roughly consistently an egg will develop inside one of your ovaries. As it achieves development, the egg is discharged by the ovary where it enters the fallopian tube to advance towards sitting tight for sperm and the uterus. In other words Ovulation is the arrival of egg from the ovaries. In people, this occasion happens when the de Graff’s follicles crack and discharge the auxiliary oocyte ovarian cells. After ovulation, amid the luteal stage, the egg will be accessible to be prepared by sperm. What's more, the uterine coating (endometrium) is thickened to have the capacity to get a prepared egg. In the event that no origination happens, the uterine coating and in addition blood will be shed amid feminine cycle.
Polycystic ovary syndrome (PCOS) is a hormonal condition that affects how your ovaries work. Usually, about five follicles start to mature during each menstrual cycle. At least one follicle releases a mature egg at ovulation. A polycystic ovary starts to mature at least twice as many follicles as normal, most of which enlarge and ripen but do not release an egg. It is estimated that between 22 and 33 per cent of women have polycystic ovaries. Some women go on to develop polycystic ovary syndrome (PCOS), which means they have other symptoms in addition to polycystic ovaries. PCOS happens when their hormonal system gets out of balance, making ovulation rare or irregular, and causing other changes in the body. Polycystic ovary syndrome is estimated to affect between five and 15 per cent of women of reproductive age, and it is thought to be more common in women of Asian descent. The exact cause of the problem is unknown but it's likely to be a combination of factors. Genetics are involved, as PCOS tends to run in families. Having higher than normal levels of the hormone insulin in your body is linked to PCOS.
Cancer is a widespread disease leading to millions of deaths each year. Thus, creating a in suppressible need of market analysis of cancer around the world. The worldwide rise in geriatric population and increasing incidence of cancer even in young adults is alarmingly strikes the need of a thorough study of patterns associated with cancer incidence. With increasing cancer patients and recent advancements in the research of cancer cure, there is a booming rise in the market for cancer research.
With rising awareness and inclined dependency on chemotherapy for cancer cure, the pharmaceutical corporations have a noted to have boomed with a skyrocketing rise.
20% of death in the Europe is due to cancer and it is home for the one quarter of cancer patients worldwide with an increase of 3.7 million new patients every year. While U.S stands second after Europe in death due to cancer.
Although, ways to prevent cancer is still not discovered, with the available technology, complete cancer cure is much nearer than ever before. It is hoped that by 2026, there will be more cancer survivors in the battle against cancer and it is predicted more than 20.3 million people suffering from cancer shall by recovered.
Only in the year of 2017, US, has been said to spent around $147.3 billion in the research of Cancer.
Tobacco is still the major cause of cancer and it is estimated that more than 80% - 90% of cancer death is due to taking one or another form of Nicotine. While in several nations, radiation is marked as the major cause of cancer deaths.
The view on cancer and cancer care research is now experiences a positive change all around the world. A multiple option like gene therapy, hormonal therapy, immunotherapy, radiation therapy is now available apart from the cultural chemotherapy. Surgeries for cancer is well received and, in most countries, more than one option is provided to give a combined effect to give a better fight against cancer.
In the last decade, more than 70 new oncology cure or treatments have been developed, associated with biomarkers, gene regulations and are used to treat more than 20 different tumours.
In 2020, the Annual global growth rate of drug market of oncology is expected to be risen from 7.5% - 10.5%, reaching a margin of $150 billion. Over the years, the cancer drugs have also shown an increased rate, leading to the rise in the oncology drug market.