CPD Accredited 6th International Conference on Drug Discovery and Drug Development

Madrid, Spain

December 7-9, 2023

We warmly welcome you all from all over the world to attend the conference entitled “The 6th International Conference on Drug discovery and drug development scheduled during December 07-09, 2023, which is going to be held in Madrid, Spain.

Drug Development Conference 2023 will serve as a global forum for debating, exchanging, and exploring new fields of research and development as well as for learning about emerging technologies and algorithms in Drug development.

Drug Development Conference 2023 would be a fantastic chance to learn more about pharmacy-related topics and gain practical experience. A group of worldwide leaders in the developing pharmacy practice sectors will be gathered at this International Conference.

The program includes keynote addresses, lectures, interactive workshops, poster presentations, and exhibitions.

Keep in touch with us throughout Drug Development Conference 2023 to help us stay proactive and help Clinical Pharmacy's future take form.

We look forward to your presence in Madrid, Spain.

Best regards,

Drug Development Conference 2023,
Organizing Committee.

Session 01. Pharmaceutical Sciences

The drug sciences are a gathering of interdisciplinary spaces of study worried about the plan, activity, conveyance, and attitude of medications. They apply information from science (inorganic, physical, biochemical, and insightful), science (life systems, physiology, natural chemistry, cell science, and sub-atomic science), the study of disease transmission, measurements, chemometrics, math, physical science, and synthetic designing.

The drug sciences are additionally partitioned into a few explicit fortes, with four primary branches:

• Pharmacology:  The investigation of the biochemical and physiological impacts of medications on individuals.

• Pharmacodynamics:  The investigation of the cell and sub-atomic connections of medications with their receptors. Just "How the medication deals with the body"

• Pharmacokinetics:  The investigation of the components that control the grouping of medication at different destinations in the body. Essentially "How the body deals with the medication"

• Pharmaceutical toxicology: The investigation of the destructive or poisonous impacts of medications.

• Pharmacogenomics:  The investigation of the legacy of trademark examples of communication among medications and organic entities.

• Pharmaceutical science:  The investigation of medication configuration to enhance pharmacokinetics and pharmacodynamics, and amalgamation of new medication atoms (Medicinal Chemistry).

• Pharmaceutics:  The examination and plan of medication detailing for ideal conveyance, soundness, pharmacokinetics, and patient acknowledgment.

• Pharmacognosy:  The investigation of prescriptions got from normal sources

Session 2:  Drug discovery

This research topic aims to publish data on recent advances in early Drug Discovery against emerging/neglected tropical diseases, including parasitic, bacterial, viral, and fungal infections Here, we gather insightful data on the creation of fresh experimental methods, the discovery of fresh therapeutic plans, and the mode of action of traditional or cutting-edge antibacterial substances.

Over the past 40 years, the complexity of drug development has multiplied, necessitating the preclinical stage of drug research, an investigational new drug (IND) application, and extensive clinical testing before FDA marketing clearance. Successful  Drug Discovery is like finding a safe and effective oasis in a chemical and biological desert. Because deserts are huge and oases are tiny, analyses based on the drug development strategy reveal that the discoverability of viable candidates is extremely sensitive to the accuracy of predictions. Especially since  Drug Discovery is very difficult to measure late in the process before the project succeeds or fails.

    Discovery Development
    Preclinical research
    Drug development process
    Market  monitoring

 Session 3: Drug Development

Once a lead molecule has been found through the process of drug discovery, the process of drug development is used to bring a new pharmaceutical medicine to market. Preclinical research on microbes and animals is part of this process, as is requesting regulatory status, such as through the US Food and Drug Administration, to begin human clinical trials for an investigational new drug. It may also include the step of securing regulatory approval with a new drug application to market the drug. It normally takes more than ten years for a vaccine or medication to be approved, from concept to preclinical testing in the lab to clinical trial development, including Phase I-III trials.

Session 4: FDA Drug Review

The structural similarities between the FDA's drug reviews and many other regulatory bodies' judgments include high uncertainty, low reversibility, avoiding observable error, and high political stakes that encourage lobbying by interested parties. This essay investigates the policy implications of considering FDA drug evaluation as a politically motivated information processing activity. I contend that the incentives regulators face place restrictions on how quickly medication reviews may be completed, that these motivations may make privatization efforts difficult, and that political pressures may be helpful in identifying high-priority pharmaceuticals.

·         Pharmaceuticals

·         Disease

·         Politics

·         HIV\ AIDS

·         Prescription Drug Costs

Session 5:  Drug Discovery and Screening

The Drug Discovery Process involves many different stages and series of actions. Typically, it can be divided into four main stages: Early Drug Discovery, Pre-Clinical Phase, Clinical Phases, and Regulatory Approval. Let's explore the major steps that are taken in each of these stages to develop a new drug.

Drug discovery is a process where a new drug or medication is discovered and aims to identify a compound therapeutically useful in curing and treating disease. It includes a wide range of scientific divisions, including biology, chemistry, and pharmacology. This process associates with the identification of candidates, synthesis, characterization, validation, optimization, screening, and assays for therapeutic efficacy.

Drug screening is a process where potential drugs are identified and optimized before the selection of a candidate drug to progress to clinical trials. It can involve screening large volumes of chemicals for a particular biological activity in high-throughput screening assays. Drug screening mainly includes In-vivo and In-vivo models drug screening.

·         Discovery and Development.

·         Preclinical Researches

·         Clinical Researches

·         FDA Review.

·          FDA Post-Market Safety Monitoring.

Session 6 : Clinical trial in Drug Discovery

Today, people are living longer because of the success of cancer treatments resulting from previous clinical trials. Through clinical trials and drug discovery, doctors determine whether new treatments are safe, effective, and better than current treatments. Participating in clinical trials broadens our knowledge about cancer and helps improve cancer care for future patients. In this way, clinical trials play a major role in the drug development and Drug Design process.

 Helps improve treatment. Clinical trials are key to advancing the fight against cancer. In today's global scientific age, clinical trials and drug Discovery are essential to bringing newer and better medicines to market. Clinical trials test potential treatments on human volunteers (subjects) to determine whether they should be approved for wider use in the general population. For the future of better healthcare, Clinical Trials are important.

Prevention trials

Treatment trials

case-control studies

Cross-sectional studies

Session 7:  FDA Post-Market Drug Safety Monitoring

Despite the fact that data from clinical trials is crucial for understanding a drug's efficacy and safety, it is difficult to know everything there is to know about a drug's safety at the time of approval. There are restrictions despite the meticulous processes in the drug development process.

 As a result, throughout the weeks, months, and sometimes even years that make up a product's existence on the market, the true image of that product's safety actually changes. When FDA receives reports of concerns with prescription and OTC medications, it may decide to add warnings to the dosage or usage instructions or take other action in the case of more serious problems.

In this session You Will find information on:

·         Supplemental Application

·         INDs for Market Drugs

·         Manufacturer Inspections

·         Generic Drugs

·         Reporting Problems

Session 8:  History Of Drug Discovery

 Drug discovery and development has a long history and dates back to the early days of human Civilization. The first synthetic drug, chloral hydrate, was discovered in 1869 and introduced as a sedative-hypnotic; it is still available today in some countries. Ancient people in what is now Switzerland ate poppy seeds (the source of opium) in 2500 BCE. Coca leaves (the source of cocaine) have been chewed for thousands of years. Folk medicines made from plants and herbs have also been used since ancient times. People in ancient Palestine drank wine in 350 BCE.

·         Chinese Medicine

·         Indian  Medicine

·         Greek  Medicine

·         Roman  Medicine

Session 9: Advanced Drug Delivery System

An advanced drug delivery system is also termed a Novel drug delivery system which improves drug potency, controls drug release to give a sustained therapeutic effect, and provides greater safety then finally it targets a drug specifically to the desired tissue. Drug Delivery systems are developed to deliver a required amount of drugs effectively to appropriate target sites and to maintain the desired drug levels

Innovative Drug Delivery Technologies

Implantable Drug Delivery System

Pediatric Drug Delivery systems

Routes of Drug Administration

Session 10:  Future trends impacting the pharmaceutical industry

Gene and cell therapies could make strong advancements in 2021 providing a new approach to treating diseases. Cancer treatments have been advancing at an accelerated pace, offering clinical benefits and increased specificity through engineered cell or gene therapies. The Indian pharma industry is expected to grow to $130 billion by 2030 and become the leading provider of medicines to the world, said Indian Pharmaceutical Alliance (IPA) Secretary General, Sudarshan Jain on Thursday.

Top  Pharma Trends in 2022

·         Artificial Intelligence

·         Big Data & Analytics

·         Flexible Production.

·         Precision Medicine

·         Additive Manufacturing

·         Blockchain

·         Extended Reality (XR)

Session 11: Targeted Drug Delivery

Targeted Drug Delivery, at times called keen medication delivery, is a strategy for conveying a prescription to a patient in a way that expands the grouping of the drug in certain pieces of the body compared with others. This method for conveyance is to a great extent established on nanomedicine, which intends to utilize nanoparticle-intervened drug conveyance to battle the destructions of ordinary medication conveyance.

 These nanoparticles would be stacked with medications and focused on explicit pieces of the body where there is exclusively sick tissue, in this manner staying away from collaboration with solid tissue. The objective of a focus on drug conveyance framework is to drag out, confine, target, and have secured drug cooperation with the ailing tissue.

The traditional medication conveyance framework is the ingestion of the medication across a natural layer, though the focus on the discharge framework delivers the medication in a dosing structure. The benefits of the focused-on-discharge framework are a decrease in the recurrence of the measurements taken by the patient, a more uniform impact of the medication, a decrease in medication results, and diminished variance in flowing medication levels. The impediment of the framework is a significant expense, which makes efficiency more troublesome and the diminished capacity to change the measurements.

Session 12: Pharmaceutical Packaging

Pharmaceutical Packaging is the bundles and the bundling measures for drug arrangements. It includes the entirety of the activities from creation through drug appropriation channels to the end shopper. Drug bundling is exceptionally directed yet with some variety in the subtleties, contingent upon the nation of beginning or the locale.

 A few normal variables can include: confirmation of patient wellbeing, affirmation of the viability of the medication through the expected time span of usability, consistency of the medication through various creation parts, careful documentation, all things considered, and measures, control of the conceivable movement of bundling segments into the medication, control of corruption of the medication by oxygen, dampness, heat, and so forth, avoidance of microbial defilement, sterility, and so on Bundling is frequently associated with apportioning, dosing, and utilization of the drug item. Correspondence of legitimate use and preventative marks are additionally managed. Bundling is a basic piece of drug items.

 Session 13.  Pharmacovigilance And Drug Safety :

Pharmacovigilance is also called drug safety, it is a pharmacological science that is related to the detection, collection, assessment, monitoring, and prevention of adverse effects with therapeutic products. The term "Pharmacovigilance" originated from Pharmakon (Greek for drug) and Vigilare (Latin for to stay watch).

 It usually focuses on adverse drug reactions, or ADRs, that are defined as any response to a drug that is toxic and undesirable, including lack of efficacy. Therapeutic errors like high doses, misuse, and abuse of a drug as well as drug exposure during pregnancy and breastfeeding, are significant.

Drug Safety

Advanced Methods in Pharmacovigilance

Artificial Intelligence in Pharmacovigilance

Ecopharmacovigilance

Substance-Based Medical Devices.

 Session 14.Pharmaceutical Industry:

The pharmaceutics 2023 industry discovers, develops, produces, and markets drugs or pharmaceutical drugs for use as medications to be administered to patients. , with the aim to cure them, vaccinate them, or alleviating symptoms. Pharmaceutics 2023 companies may deal in generic or brand medications and medical devices.

They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy using drug testing, and marketing of drugs. The global pharmaceutics 2023 market produced treatments worth $1,228.45 billion in 2020 and showed a compound annual growth rate (CAGR) of 1.8%.

Pharmaceutical R&D

Orphan Drugs

Drug Development and Manufacturing

Drug Marketing

Industrial Safety and Efficacy.

Session 15 : Pharmacogenomics(Genomic Approaches to Drug Discovery)

The branch of genetics is concerned with how a person's genetic characteristics influence their likelihood of responding to therapeutic medications. Pharmacogenomics is likely to lead to improved drug management for heart disease, cancer, asthma, depression, and a variety of other diseases soon. It also intends to eliminate the trial-and-error approach to prescription by pushing clinicians to learn about their patient's genes, how they work, and how this may affect the efficacy of their current or future medicines.

Drug therapy

Challenges of pharmacogenomics

Pharmacogenomics in clinical therapeutics

Cancer pharmacogenomics

Pharmacokinetic aspects

Clinical efficacy and safety evaluation

Session 16: Current Market and Technology

The high prevalence rate of health diseases, the implementation of drug discovery, and bioinformatics technology are the factors driving the drug discovery industry.

The technologies and drug types are widely used for a variety of reasons. High Throughput Screening (HTS) approaches enable the pharmaceutical industry to screen vast libraries of drugs. Combinatorial chemistry is the process of creating many structurally different molecules. Nanotechnology-based drug discovery resolutions are beginning to produce significant new perspectives of how biological systems work.

Global drug delivery market

New technologies

Metabolomics

Biochips

Nanotechnology

Session 17: Translational Medicine

Our patients and their diseases are the driving force behind translational medicine. Translational research spans the spectrum from molecular and cell biology through preclinical models to patient investigations and back again, guided by this fundamental goal. Encourages and promotes laboratory and clinical researchers to collaborate across disciplines. Incorporates public wishes, with communities being involved in determining their requirements for health innovation. Identifies and promotes the use of the most effective medical and health practices.

Human diseases

Dissemination research

Diffusion research

New treatment and approaches to medical care

Session 18: Pharmaceutical Industry

The pharmaceutical industry is the discovery, development, and manufacture of drugs and medications (pharmaceuticals) by public and private organizations. The pharmaceuticals industry consists of drug manufacturers, biotechnology companies, and the distribution and wholesale companies that handle the products produced. Companies making related products, such as vitamins, other health supplements, or diagnostic substances, are also included.

Research and development

Global sales and marketing

Challenges that face the pharmaceutical industry

Pharma companies

Session 19: Transdermal drug delivery system

Transdermal therapy systems are defined as self-contained, self-contained dosage forms that, when applied to undamaged skin, release the drug to the systemic circulation at a controlled rate. A simple patch that adheres to your skin like an adhesive bandage and uses passive medication diffusion across the skin as the delivery mechanism.

Skin-MediatedTherapies and Vaccines

Risk-BasedStrategies

Cosmeceuticals

Latest advances in TDDS

Session 20: Toxicology

Toxicology is the scientific study of the harmful effects of substances on living beings. It entails observing and reporting symptoms that emerge because of toxic material exposure. Toxicology studies are used in the drug development process to assess the safety of possible medication candidates. This is done with the help of relevant animal models and tried-and-true methodologies. The goal is to translate the animal responses into an understanding of the risk for human subjects

Toxicogenomic

Clinical toxicology

Chemical toxicology

Medical toxicology  

The global drug discovery market size was valued at US$ 74.96 billion in 2021 and is expected to be worth around US$ 161.76 billion by 2030, growing at a CAGR of 8.9% from 2021 to 2030.

 

Growth Factor :

 

The global drug discovery market is significantly driven by the rising prevalence of various chronic diseases, rising healthcare expenditure, and patent expiration of certain popular drugs across the globe. The global population is facing growing burden of various diseases such as cardiovascular diseases, diabetes, cancer, respiratory diseases, and neurological disorders, which is significantly fueling the demand for the new and innovative drugs. The exponentially growing pharmaceutical industry owing to the rapid growth of the biopharmaceuticals is expected to drive the drug discovery market in the forthcoming years. The biopharmaceutical industry is growing at a rapid pace owing to the rising investments by the government and corporate for the development of new medicines to treat chronic diseases. Moreover, the favorable government regulations coupled with the active role of the authorities such as FDA and EMA is fueling the market growth.

The changing lifestyle, shifting consumption pattern, unhealthy food habits, rising pollution levels, and physical inactivity is resulting in the growing burden of various diseases like cancer, diabetes, and cardiovascular diseases. According to the International Agency for Research on Cancer, around 19.3 million new cancer cases and around 10 million cancer deaths were reported in 2020. As per the International Diabetes Federation, around 783 million people across the globe are estimated to live with diabetes by 2045. Further, over 1.2 million children and teenagers are suffering from type 1 diabetes. According to the World Health Organization, the cardiovascular diseases results in almost 18 million deaths each year and it is the leading cause of death across the globe. Thus, the demand for the innovative drugs that can cure chronic diseases is high among the global population, which in turn fuels the growth of the drug discovery market. The rising investments by the pharmaceutical companies in the research & development of various new drugs and clinical trials research is expected to propel the growth of the global drug discovery market.

Some of the prominent players in the global drug discovery market include:

• Pfizer Inc.
• GlaxoSmithKline PLC
• Merck & Co. Inc.
• Agilent Technologies Inc.
• Eli Lilly and Company
• F. Hoffmann-La Roche Ltd
• Bayer AG
• Abbott Laboratories Inc.
• AstraZeneca PLC
• Shimadzu Corp.

Drug Discovery Market, By Drug Type

• Small Molecule Drugs
• Biologic Drugs

Based on Drug Type, The market is segmented into Small-Molecule Drugs and Biologic Drugs. Small Molecule Drugs are predicted to account for the biggest market share during the forecasted period since they are simple, well-defined, and straightforward to characterize. Because of these characteristics, they can penetrate cells fast, alter molecules, and cause cancer cells to die. Small molecules continue to play an important role in the development of new medicines in four core therapeutic areas: oncology, cardiovascular illness, autoimmune disease, and respiratory diseases. The potential of small molecules in the pharmaceutical portfolio is enhanced by their increased relevance and highly effective components. All of these reasons are expected to drive segment expansion.

Drug Discovery Market, By Technology

• High Throughput Screening
• Pharmacogenomics
• Nanotechnology

Based on Technology, the market is segmented into High Throughput Screening, Pharmacogenomics, and Nanotechnology. Technology is important in all aspects of small molecule Drug Discovery, from target selection and validation to lead optimization. As a result, technical improvements have been a driving force in the sector. The ongoing focus resulted in an increase in the number of targets identified, validated, and drugs developed.

Report Scope

REPORT ATTRIBUTES	DETAILS
STUDY PERIOD	2018-2030
BASE YEAR	2021
FORECAST YEAR	2023-2030
HISTORICAL PERIOD	2018-2020
UNIT	Value (USD Billion)
KEY COMPANIES PROFILED	Pfizer Inc., GlaxoSmithKline PLC, Merck & Co. Inc., Agilent Technologies Inc., Eli Lilly and Company, F. Hoffmann-La Roche Ltd, Bayer AG.
SEGMENTS COVERED	By Drug Type, By Technology, By End-Users, And By Geography.
CUSTOMIZATION SCOPE	Free report customization (equivalent up to 4 analyst’s working days) with purchase. Addition or alteration to country, regional & segment scope

 

Scope of the Report

According to the scope of the report, Drug Research is the process aimed at identifying  therapeutically useful compounds for the treatment and cure of disease. Drug discovery usually begins with molecules that either address biological targets that have been shown to be involved in disease development  or have interesting biological activities. In recent times, drug discovery has advanced significantly with new technologies that have made the process  more sophisticated, more precise, and less time consuming. The drug discovery market is divided by drug type (small molecule drugs and biologics), technology (high-throughput screening, pharmacogenomics, combinatorial chemistry, nanotechnology, and other technologies), and end users (pharmaceutical companies, contract research organizations (CROs)). ) etc.). end users), Geography (North America, Europe, Asia Pacific, Middle East, Africa, South America). The market report also includes estimated market size and trends for 17 countries in key regions of the world. This report provides the value (Million USD) for the above segment.