2^ndAnnual summit on
Tuberculosis and Lung disease

Atlanta, USA

July 16-17, 2018

The 2^nd Annual summit on Tuberculosis and Lung disease will be held in Atlanta, USA during July 16-17, 2018. It will bring together world-class pulmonologist, scientists and professors to discuss strategies for disease remediation for TB & lung diseases in this conference. Annual summit on Tuberculosis is designed to provide a diverse and current education that will keep medical professionals up to date on issues affecting the diagnosis, treatment of respiratory disorders and prevention.

The conference theme "A new way to battle with Tuberculosis and Lung disease" that focuses to share novel approaches related to the field and exploring the challenges concerning excellence in TB research and advancements.

2^nd Annual summit on Tuberculosis and Lung disease is an extraordinary event designed for TB experts and international medical health professionals to facilitate the dissemination and application of research findings related to TB and all the associated research areas. The conference invites participants from universities, clinical research institutions and diagnostic companies to share their research experiences on all aspects of this rapidly expanding field and thereby, providing a showcase of the latest techniques.

Scope and importance:

Our aims to provide tuberculosis physicians, specialists, nurses, technologists and anyone professionally involved in respiratory disease with an opportunity to learn about the complexity of the disease, discuss interventional procedures, look at new and advanced TB practices and their efficiency and efficacy in the treatment of various cases, and understand local realities and practical constraints in improving patient-care.

Why to attend??

With people across the globe focused on finding a few solutions concerning TB and lung diseases, this is the best platform to meet the eminent personalities of respiratory care. This scientific stage will allow the researcher to showcase their research work through presentations and have a chance to gain knowledge about the current situation of lung disease treatment and receive name recognition at this 2-day event.

Greatest achievements in the field of TB:

The great achievement in lowering tuberculosis rates during the last decades of the 20th century are secondary to the extraordinary advances made in the understanding of basic respiratory science and in the enlargement of new diagnostic and therapeutic techniques. The most important cardiologic developments and discoveries of the last century are Multidrug-resistant TB (MDR-TB); first-line and second-line anti-TB drugs; DOTS (directly observed treatment-short course) therapy and Short course chemotherapy (SCC); “Stop TB” strategy; RNTCP (revised national TB control program). The development and widespread implementation of vaccination against TB ranks one amongst man’s greatest achievements.

Target Audience:

Pulmonologist

Lung cancer Surgeons

Scientists and Researchers

Medicinal Practitioner

University Professors

Lung & respiratory associations and their members

Tuberculosis Societies and their members

Founders and Employees of health-related companies

Experts of TB control Program

Medicine, TB and pharma institutes

Training Institutes

Physicians interested in the latest advances and techniques

Research Scholars and Students

Pharma Companies

Allied Academic Publication is an amalgamation of several esteemed academic and scientific associations known for promoting scientific temperament. Established in the year 1997, Andrew John Publishing Group is a specialized Medical publisher that operates in collaboration with the association and societies.  This publishing house has been built on the base of esteemed academic and research institutions including The College of Audiologists and Speech Language Pathologists of Ontario(CASLPO), The Association of Public Safety Communications Officials of Canada (APCO), The Canadian Vascular Access Association (CVAA), The Canadian Society of Internal Medicine (CSIM), The Canadian Hard of Hearing Association (CHHA), Sonography Canada, Canadian Association of Pathologists (CAP-ACP) and The Canadian Association of Neurophysiologic Monitoring (CANM).

On behalf of Allied academics we are glad to invite you to 2nd Annual summit on Tuberculosis and Lung disease held at Atlanta, USA during 16-17 July 2018. Our conference proceeds with theme “A new way to battle with Tuberculosis and Lung disease”. The conference deals with re-emerging of TB and Lung diseases & explore new ideas/concepts on a global scale to reduce the airborne disease and the topics include complications, treatment and therapies for lung infections and tuberculosis,  Present scenario and risk factor of infection, Clinical trials in respiratory diseases, TB Education and Research.

It provides a platform for refreshing your knowledge and forecast future developments in clinical research. This conference will offer you plenty of opportunities to meet world’s leading scientists and researchers.

Annual summit on Tuberculosis and Lung disease is best source for business network expansion; we also invite worldwide pharmacy, life science and research laboratory industries as sponsors and exhibitors.

We are excited to meet you in Atlanta at our conference meet & we hope you will join us at our scientific meet to expand your knowledge and move forward in your research.

Track 01: Mycobacterial infections

Tuberculosis is a chronic inflammatory infectious disease caused by the bacteria, Mycobacterium tuberculosis. Tuberculosis generally affects the lungs, but can even affect other parts of the body. Most infections are asymptomatic, known as latent tuberculosis. About 10% of latent infections progress to active disease, if left untreated, mostly kills about half of those infected. Symptoms of active TB are chronic cough with blood-containing sputum, night sweats, one weight loss and fever. Infection of other organs can cause a wide range of symptoms including bones and joint pains, chest pain, neurological disorders and chronic pulmonary or respiratory distress etc.

Tuberculosis Conference | Lung Conference | Asthma Conference | Pneumonia Conference | Pulmonary Conference | Respiratory infections Conference

Track 02: Epidemiology of the Disease

Tuberculosis epidemiology is the field of science that is concerned with the study of health and disease within populations and the various factors that lead to these conditions, with a goal of preventing the spread of disease. One-third of the world's population has been infected with M. tuberculosis. 13.7 million Chronic active cases, were reported by 2007 and 8.8 million new cases were estimated in 2010 and 1.45 million deaths, are often noted in developing countries.  Out of these, 0.35 million deaths occur in those co-infected with HIV. In 2012, around 450,000 people developed MDR-TB. TB incidence varies with age. In Africa, TB chiefly affects adolescents and young adults. However, in United States, TB has gone from high to low incidence, where TB is mainly a disease of older people, or of the immunosuppressed.

Since 1985, Lung cancer has been the most common cancer in the globe. Worldwide, lung cancer, new cancer diagnosis (134 thousand people and 12.4% of new cancer patients) and cancer fatalities (1,180,000 deaths, 17.6% total cancer deaths). COPD is the fourth leading cause of death in the United States and is related to age. Lung cancer increases with age, especially after age 60. The average age of patients diagnosed with lung cancer is 70 years.

Tuberculosis Conference | Lung Conference | Asthma Conference | Pneumonia Conference | Pulmonary Conference | Respiratory infections Conference

Track 03: Genetics of M. tuberculosis

In 1998, the genome of the H37Rv strain was published. The size of the genome is 4 million base pairs, and has 3959 genes, out of these 40% of genes have their function characterised and another 44% are postulated with possible functions. Six pseudo genes are present within the genome.

Genome contains 250 genes involved in fatty acid metabolism, with 39 of these involved in the polypeptide metabolism generating the waxy coat. Such vast numbers of conserved genes show the revolutionary importance of the waxy coating to pathogen survival. M. tuberculosis can grow on the lipid cholesterol as a sole source of carbon, as genes involved in the cholesterol use pathways that have been important during various stages of the infection with tuberculosis. 10% of the coding genes are taken up by the amino acids that encode acidic, glycine-rich proteins. These proteins have a conserved N-terminal motif, deletion of which leads to impaired growth in granulomas and macrophages.

Tuberculosis Conference | Lung Conference | Asthma Conference | Pneumonia Conference | Pulmonary Conference | Respiratory infections Conference

Track 04: Pulmonary Diseases and Therapeutics

Advanced diagnostic techniques such as X-ray and echocardiography is used to diagnose lung diseases and lung function tests (PFT) is another test to determine lung cancer disease. This is a medical process involving the pleural cavity and other thoracic internal examination, biopsy and resection of the disease or mass. Thoracoscopy may be sedation under general anesthesia or local anesthesia. Surgical biopsy is a better way to diagnose lung cancer standards. Must wear appropriate masks & monitor exposure and in some working environments it is important to take precautions. Chronic obstructive pulmonary disease is a gradual process that causes difficulties in the death of respiratory failure or its associated lung disease (including respiratory arterial disease, lung cancer, stroke and smoking cessation) and is the process of stopping smoking. Tobacco contains nicotine, which is addictive; in the process of smoking cessation, can be controlled by vaccination and prophylaxis.

Tuberculosis Conference | Lung Conference | Asthma Conference | Pneumonia Conference | Pulmonary Conference | Respiratory infections Conference

Track 05: Lung infection

A Lung infection affects lungs, either in the larger airways (bronchitis) or in the smaller air sacs (pneumonia). There is a build-up of pus and fluid (mucus), and the airways become swollen, making it difficult for to breathe. Chest infections can affect people of all ages. Young children and the elderly are most at risk, as well as people who are ill and smokers. A chest infection can be serious for these people.

Tuberculosis Conference | Lung Conference | Asthma Conference | Pneumonia Conference | Pulmonary Conference | Respiratory infections Conference

Track 6: Vaccines & Immunization

As of 2011, the only available vaccine is Bacillus Calmette-Guérin (BCG), is a vaccine for (TB) tuberculosis disease. Many people have been BCG-vaccinated. BCG is primarily used as vaccine in many countries with a high aid for preventing TB as childhood tuberculous meningitis and miliary disease. Tuberculosis can be treated by taking several drugs for 6 to 9 months.  There are 10 drugs presently approved by FDA (U.S. Food and Drug Administration) for treating TB. Out of the approved drugs, the first-line anti-TB agents that form the basis of treatment regimens include: isoniazid, pyrazinamide rifampin, ethambutol, streptomycin. Once the TB patient is known to be fully susceptible to ethambutol or streptomycin, it can be discontinued.

Directly observed therapy (DOT) is mainly recommended for all the patients. With DOT treatment, patients with the above regimens can shift to 2 to 3 times per week dosage after an initial 2 weeks of daily dosing. Patients on twice-weekly dosing should not miss any doses. Require daily therapy for patients on self-administered medication.

Tuberculosis Conference | Lung Conference | Asthma Conference | Pneumonia Conference | Pulmonary Conference | Respiratory infections Conference

Track 7: TB Clinical Trials

Clinical trials are concerned with diagnosis and treatment of the disease. The development of drug-resistant TB (XDR-TB) and multidrug-resistant TB (MDR-TB) are extensively a rising global health problem. A recent advance in the progress of new drugs & regimens provides hope that may be well effective, tolerated and shorter-duration treatment for tuberculosis will become available. During clinical trials they promote research within local TB control programs through association on clinical research of importance to public health settings, and to provide a platform for international collective research of consequence to both domestic and universal TB control.

Rapid urine-based screening for Tuberculosis in hospitalised patients in Africa to reduce AIDS-related mortality. Thibela TB is the mass screening and treatment plan in mining communities, The ZAMSTAR trial is the community TB testing and counselling, Diabetes correlated with increased risk of TB in the United Kingdom are some of the latest clinical trials or the projects going-on to reduce the risk of Tuberculosis.

Tuberculosis Conference | Lung Conference | Asthma Conference | Pneumonia Conference | Pulmonary Conference | Respiratory infections Conference

Track 8: Resistance to TB Drugs

Multidrug-resistant TB (MDR-TB) begins when an antibiotic fails to eradicate all the bacteria that it targets, with the surviving bacteria producing resistance to that antibiotic and usually others at the same time. Primary Multidrug resistant, MDR-TB occurs in patients who was not earlier been infected with TB but who became infected with a strain which is resistant to the treatment. Acquired multidrug resistance for TB occurs in patients during treatment with a drug regimen that is not competent of killing the particular strain of TB with which they have been infected. MDR-TB requires treatment with second-line drugs, often four or more anti-TB drugs for a minimum of 6 months and a maximum for 18–24 months, if rifampin resistance has been identified in the specific strain of TB with which the patient has been infected. Under ideal program conditions, MDR-TB cure rates can approach 70%. In general, second-line drugs are less effective, more toxic and much more expensive than first-line drugs.

Tuberculosis Conference | Lung Conference | Asthma Conference | Pneumonia Conference | Pulmonary Conference | Respiratory infections Conference

Track 9: TB Co-infections

TB and HIV co-infection is that where people have both, either latent or active TB disease and also HIV infection. In addition to HIV infection is speeding up the progress from latent TB infection to active TB disease, in accordance TB bacteria also enhance the progression of HIV infection. Than many other opportunistic infections, TB occurs earlier in the course of HIV infection. In co-infected individuals, the risk of death is also twice that of HIV infected individuals without TB, even when antiretroviral therapy and CD4 cell count are taken into account. The provision of anti TB drug therapy and HIV antiretroviral treatment at the same time involves a number of potential difficulties including: A high pill burden, Drug – drug interactions, Cumulative drug toxicities.

TB and Diabetes co-infection: Poorly controlled diabetes can lead to numerous complications, including neuropathy, vascular disease, and increased susceptibility to infection. Diabetes may also lead to increased susceptibility to the disease via multiple mechanisms that are caused by M. tuberculosis.

There are even other co-infections with Tuberculosis such as malaria, Typhoid fever, Dengue, hepatitis.

Tuberculosis Conference | Lung Conference | Asthma Conference | Pneumonia Conference | Pulmonary Conference | Respiratory infections Conference

Track 10: TB diagnosis/ Prevention & Treatment

TB diagnosis includes microbiological studies such as sputum, alternative sampling, PCR.  Immunological test involves ALS assay, transdermal patch, tuberculin skin test, mantoux skin test, heaf test, CDC classification of tuberculin reaction, BCG vaccine and tuberculin skin test, Adenosine deaminase, Nucleic acid amplification tests (NAAT), Full blood count & Interferon-? release assays.

TB prevention and control efforts depend primarily on the vaccination of infants and the detection & treatment of active cases. The World Health Organization (WHO) has achieved some success with rapid diagnostics and improved treatment regimens. US Preventive Services Task Force (USPSTF) endorses screening those who are at high risk for latent tuberculosis with either mantoux tuberculin skin tests or interferon- ? release assays. Prevention of TB consists of two main parts. The first part of preventing TB is to cease the transmission of tuberculosis from one person to another. This can be done firstly, by identifying people with active TB infection, and then curing them by providing the drug treatment. With the provision of proper TB therapy someone with TB will not be infectious very quickly, and so cannot spread the disease to others. The second main part of preventing TB is to prevent people with latent TB infection from developing active infectious TB disease.

Tuberculosis Conference | Lung Conference | Asthma Conference | Pneumonia Conference | Pulmonary Conference | Respiratory infections Conference

Track 11: Zoonotic TB

Mycobacterium bovis is the main causative agent of bovine tuberculosis (BTB) that causes zoonotic tuberculosis (TB) in humans. Bovine TB is mostly acquired from domestic animals and their products, in which cattle’s are the major reservoir. The disease results in huge economic loss, particularly in urban and per-urban cross breed dairy cattle due to mortality, low productivity and carcass condemnation as well as trade restrictions of live animals, products and by products of animals. To prevent and control zoonotic TB, veterinary sectors must be cross sectored in controlling the disease in its animal reservoir, developing diagnostic tools for diagnosing M. bovis, strengthening surveillance systems and assessing economic impact.

Tuberculosis Conference | Lung Conference | Asthma Conference | Pneumonia Conference | Pulmonary Conference | Respiratory infections Conference

Track 12: Lung Cancer

Lung cancer is currently the leading cause of cancer-related deaths in men and women in the world. Lung cancer-related trends have been mainly related to smoking over the past several decades. In 2015, the American Cancer Society handles 221,200 new cases, diagnosed as 158,040 deaths due only to lung cancer. Risk factors for lung cancer are primarily smoking and air pollution. According to the doctor's suggestion, there are no symptoms associated with the first stage of lung cancer. According to researchers' research, lung cancer mortality rate is not improved at the time of diagnosis and most lung cancer progresses to advanced stage.

Tuberculosis Conference | Lung Conference | Asthma Conference | Pneumonia Conference | Pulmonary Conference | Respiratory infections Conference

Track 13: COPD

COPD is a disease involving airway inflammation and thickening.  It also involves the destruction of oxygen-exchanged lung tissue. The Global Initiative for Chronic Obstructive Pulmonary Disease is described as "preventable and treatable disease, characterized by an incompletely reversible airflow limitation, which is usually progressive and is associated with an abnormal inflammatory response to harmful particles or gases. This gradual and relentless loss of lung disease is caused by emphysema caused by the destruction of the lung parenchyma. Smoking (long term smokers), chronic bronchitis, genetic factors (genes) and due to chronic inflammation and fibrosis as well as elasticity The resulting loss of small airway narrows, which leads to gradual airflow limitation, air capture, and further shortages of breathing in motion.

Tuberculosis Conference | Lung Conference | Asthma Conference | Pneumonia Conference | Pulmonary Conference | Respiratory infections Conference

Track 14: Asthma & Pneumonia

Asthma is a chronic disease that makes lungs harder and affects the airways that carry air to and from the lung which leads to swelling or inflammation of the airway wall. This swelling or inflammation makes the airways extremely sensitive to irritations and increases your susceptibility to an allergic reaction. As inflammation causes the airways to become narrower, less air can pass through them, both to and from the lungs which makes difficult to breathe. Thus the patience suffers from symptoms like wheezing (a hissing sound while breathing), chest tightness, breathing problems, and coughing.

Tuberculosis Conference | Lung Conference | Asthma Conference | Pneumonia Conference | Pulmonary Conference | Respiratory infections Conference