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Allied Academies invites all the participants from all across the globe to attend " 2nd International Conference on Stem Cells and Regenerative Medicine”, on April 08 - 09, 2019 in Madrid, Spain which includes prompt keynote presentations, poster presentations, oral talks, and exhibitions. Stem cells are unique cells with an ability to differentiate in any other cells of the body. Two types of stem cells found in the body, embryonic and somatic, hold the enormous therapeutic potential to repair and regenerate damaged tissues. Regenerative medicine is an application of stem cell research which harnesses the potential of tissue engineering to stimulate repair mechanism of body and restore the damaged tissues and organs. Therefore, development of disease-specific therapies and treatments by exploiting the remarkable properties of stem cells holds hope for improvement of the quality of life and survival of patients with chronic disorders.
Objective: Stem Cell Congress 2019 is a platform to achieve the prevailing gaps in the transformation of this multidisciplinary science of hope, to serve promptly with solutions to all in the need. Stem Cell Congress 2019 will have an anticipated participation of 120+ delegates across the world to discuss the purpose of the conference.
About Organizers: Allied Academies is one of the leading Open Access publishers and organizers of international scientific conferences and events every year across USA, Europe & Asia. Allied Academies has so far organized 3000+ Global Allied Academies Events with over 600+ Conferences, 1200+ Symposiums and 1200+ Workshops on Medical, Pharma, Engineering, Science, Technology and Business with 700+ peer-reviewed open access journals in basic science, health, and technology.
Target Audience: Eminent personalities, Directors, CEO, President, Vice-president, Research scientists, Organizations, Post-docs, Associations heads and Professors, Stem Cell laboratory heads, Students and other affiliates related to the area of Stem cells research and regenerative medicine.
Sessions & Tracks
STEM CELLS: AN INSIGHT Stem cells are undifferentiated cells found in multicellular organisms which divide through mitosis and differentiate into specialized cells. The two classical properties of stem cells which allow them to differentiate into almost any kind of body cell, are self- renewal, and potency. Due to their potential role in alternative therapies, stem cells are a topic of extensive research medical science.
Biology of human embryonic stem cells.
Genomics and Proteomics in Stem Cell Biology
Cell signaling in stem cell differentiation.
In-vitro culturing of stem cells.
Applications of somatic stem cells.
MOLECULAR BASIS OF REGENERATION Regeneration is a universal phenomenon in nature by which lost cells, tissues or body parts are replaced or restored in an organism as a general process of growth. During this process, adult stem cells or progenitor cells proliferate and differentiate to compensate the loss. The ability to regenerate depends upon the potency of any cell, categorized under totipotent, pluripotent, multipotent, omnipotent and uni-potent.
Histopathology of regenerative tissues.
Hematopoietic stem cells for blood disorders.
Mesenchymal stem cells for muscular disorders.
Directed differentiation of somatic stem cells.
Neural stem cells for neurodegenerative disorders.
Tissue engineering is a multi-disciplinary science involving the principles of cell biology, engineering and material sciences to replace or restore biological tissues which perform a specific function with a better framework. It is an act of combining the cells of construct, scaffold and growth factors into a functional tissue. The feasibility of bone-marrow derived mesenchymal stem cells, cardiac valves, auricular cartilage reconstruction, etc. explains the enormous potential of this relatively new field in biomedical sciences.
Whole organ engineering.
Extracellular matrix analog.
Auricular cartilage reconstruction.
Biomaterials and biopolymers for tissue engineering.
Stem cell research laid a foundation of basic scientific perception about the development of the whole organism from a unicellular entity or single cell itself. These cells are collected from few days old embryo, amniotic fluid or many other tissues, like, bone marrow and cultured in the laboratory under biological conditions. Stem cell research is an aid of utmost important to serve as a model for genetic disorders, study DNA repair mechanisms or to design replacement therapies for practically immedicable chronic conditions.
Bone marrow transplantation and immune therapy.
Clinical research in stem cell therapy.
Approaches in clinical medicine.
Biophysical and analytical techniques in stem cell research.
Stem cell therapy is aimed at treating numerous degenerative, hematopoietic and neuromuscular disorders, nearly 80 in number which cannot be treated with conventional methods. Bone marrow transplantation for blood disorders like, leukemia is the most celebrated application of stem cell therapy, other than skin tissue grafting and implantation. This new approach in medical biology is inclined at maximizing the quality of life by reducing the adversities of chronic disorders such as cancer and genetic diseases.
Nano-biotechnology in medical sciences renders some highly convincible outcomes in which few are only envisioned, while others are at different phases of clinical trials or already in practice. Nano-biotechnology in regenerative medicine includes utilization of nano-particles which are being designed nowadays and envisioned research that involves usage of nano-robots to imply changes at cellular and molecular level. Recently, it is being used for drug-delivery, thermal- and laser therapy for cancer treatment. Particles are designed in such a way that they are easily being recognized by surface receptors of target cells to ensure direct treatment and least possible damage to unaffected cells. This technology is also exploited for detection of diseases in initial phases for devising an effective therapy.
Bio-informatics deals with the development of algorithms and databases to manage, predict and analyze biological data. In-silico analysis of small molecules as a potential drug delivery target is a preliminary step in drug designing to ensure maximum efficacy. Self- learning algorithms, like, artificial neural network, are an important tool for vaccine designing. Computational biology along with bio-informatics is a vast domain incorporating consolidated facts from computer science engineering, animation, ecology, genomics, immunology, neuroscience, biochemistry and biophysics which can be used as pre-knowledge tools for designing stem cell therapies.
Designing of tissue scaffolds.
Innovative technologies for modeling and analysis.
Certain immortal cells within the tumor are capable of proliferating into all other types of cancer cells. These cells, known as cancer stem cells, are the primary targets of cancer biologist and oncologist for treatment of various tumors, even though they are fairly resistant to chemotherapy and radiotherapy. Approaches have been made to exploit the property of these cells to develop immortal cell lines for the production of drugs and cytokines relevant to medical use, but, a lot more understanding is required before bringing the results in practice.
Prognostic and diagnostic biomarkers of cancer stem cells
The discovery of Induced pluripotent stem cells emphasizes on reprogramming of any adult differentiated cells into stem cells by genetic modification under precisely controlled laboratory conditions. Reprogramming of cells is supposed to presage revolution in both, medical and biological research and allows modeling and analysis of human diseases and cell cytotoxicity by drugs. The technique is still in its growing phase and requires a great deal of extensive research and approval from authorities for further trials.
Umbilical cord blood is highly enriched with pluripotent stem cells which are considered lifesaving in later stages of life as they can treat a host of disorders. Cord blood stem cells are used to target blood disorders, immune deficiencies, and rare metabolic disorders, including leukemia, Krabbe disease, aplastic anemia, non-Hodgkin’s lymphoma and Hodgkin’s lymphoma, sickle-cell anemia and thalassemia, with least chances of rejection by the body. Cord blood preservation of newborn babies, also termed as, stem cell banking, in public or family banks, is gaining a lot of awareness among people as it holds promise for future well-being.
The development of targeted genome editing technique using custom-engineered sequence-specific nucleases (including CRISPR/Cas9) allowed genetic changes with greater precision. This technique has a widespread application in the reprogramming of stem cells to study disease outcomes. The rapid evolution of these two techniques over years and their relationship with one another has paved a way for understanding cellular interactions and regulation of transcription at a molecular level with appreciable efficiency and flexibility.
CRISPR/Cas9 in genome editing
Genome editing for designer babies
DNA repair in stem cells
Generation of animal models by genome editing
Targeting genetic diseases by genome editing in stem cells
Stem cells and their applications in tissue regeneration comes with a few interesting controversies regarding the bioethical issues involved in stem cell research. The collection of somatic stem cells from the human fetuses and umbilical cords is the most extreme controversy so far. Other issues involve the potential of stem cells to induce a tumor in the body and use of embryos which are only few days old. Human embryo cloning was suggested as an alternative to this situation which was highly criticized by the ethical groups. Currently, lack of stem-cell markers and in-vitro systems for manipulation also hinders the research and makes it a daunting task.
Limitations and challenges in tissue engineering.
Clinical trials in alternative therapy.
Research ethics in stem cells and regenerative medicine.