Yukihiro Shoyama worked in MGH in Boston as a Post-doc in 1975. During 1978 to 1991, he worked as an Associate Professor and as a Full Professor during 1991 to 2007 in Kyushu University. During these periods he was the Director of Pharmacognosy Department, the Director of Herbal Garden, and held Deanship (2004-2006). He moved to Faculty of Pharmaceutical Sciences, Nagasaki International University as a Full Professor from 2007. He was the President of Japanese Society of Pharmacognosy (2007-2008) and Vice Chairperson of Specialty Committee of Traditional Chinese Medicine, Pharmaceutical Chemistry of World Federation of Chinese Medicine Societies (2012-2020). His research interests are marijuana studies like structure elucidation of biosynthetic enzyme protein by x-ray analysis, monoclonal antibodies against over 40 natural bioactive products, biotechnology of medicinal plants and bioactive natural products like saffron resulting in approximately 400 original papers and over 200 review articles.