Dr. Julien Reboud Photo
Dr. Julien Reboud
University of Glasgow
London
Biography
Using my experience from a PhD in France (Université Joseph Fourier/CEA) and post-doctoral work in the Institute of Microelectronics (A-STAR) in Singapore, I have established a track record in developing and integrating microfluidic systems for cell-based assays, including both high content screening for drug discovery and diagnostic tests. During my PhD, I developed a massively parallel screening platform in microdrops, using surface engineering and advanced image analysis (e.g. segmentation and statistical clustering). In Singapore, in collaboration with material scientists, I developed structures and surfaces for advanced spectroscopy techniques (e.g. Localised Surface Plasmon Resonance, Surface Enhanced Raman Scattering), as well as for diagnostics, including both immunoassays and nucleic acid-based platforms. I joined Glasgow University and the group of Prof Jon Cooper in 2009, before securing a Fellowship in 2013 as an independent researcher. Throughout my career, I have pro-actively sought to transfer technologies towards commercialisation, as evidenced through being awarded the PhD prize in the French national start-up competition (2004). In my position at IME in Singapore, I grew from lab bench researcher to project manager (as PI, co-PI and team leader) of small multidisciplinary teams, comprising post-doctoral research assistants, PhD students and technicians. I led a number of collaborations with industry, primarily aimed at integrating microfluidic systems for diagnostics and drug discovery. I have been awarded The Royal Academy of Engineering ERA Foundation Entrepreneurs prize for the work in Glasgow on acoustic techniques (2013, http://www.raeng.org.uk/prizes/era/), which has led to the spin-out company SAW Dx Ltd (www.sawdx.com). It also was the Highly Commended Technology and Innovation at the Times Higher Education Awards (2014) I have published more than 30 peer-reviewed papers in international journals, along with 15 patent applications (2 granted).
Role
OCM
CPD Accredited
World Congress on
Clinical and Medical Microbiology
Research Interests
My current research is focused on integrating engineering and biology for the benefits of healthcare and industry. More particularly, my activities can be divided into two main areas: Acoustofluidics for the manipulation of samples, with a particular emphasis on diagnostic applications, at the point-of-care. Surface acoustic waves carry a mechanical energy that can be harvested to manipulate fluids and particles (or living cells). Using advanced microtechnologies, such as phononic crystals (akin to acoustic holograms), this energy can be shaped to obtain specific functions, such as movement and mixing, fully integrated on a disposable microchip. I am interested in the development of advanced techniques to design and fabricate acoustic systems, as well as novel assay designs. A particular emphasis of this research lies with the developments of techniques for low-resource environments such as can be found in the Developing World. Acoustics offer low-cost low-power platforms to perform complex bioassays without the requirement for large infrastructures. Synthetic biology. Synthetic biology promises a modular approach to engineer products that allow new components to be discovered, tested and manufactured better, faster and cheaper than existing approaches and on a larger scale. I am interested in using advanced microfluidics and engineering to develop platforms around artificial cells to be used as complete bioreactors and sensor systems. http://www.gla.ac.uk/researchinstitutes/biology/research/synthe
Bio molecule and Microbial Biochemistry

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