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Biography

Emily K Hill is in the process of completing her MSc (Animal Biosciences) from the University of Guelph in Dr. Julang Li’s laboratory. She is scheduled to defend in August 2017 and has one publication so far. An aspiring veterinarian, she will begin her DVM degree at the Ontario Veterinary College in the Fall Semester.

Abstract

Clinically-relevant pathogens are rapidly developing resistance to conventional antibiotics making infection control difficult. Methicillin-resistant Staphylococcus aureus (MRSA) is a gram-positive bacterium commonly found to be multidrug-resistant. As infections incited by MRSA are associated with increased rates of mortality compared to drug-sensitive strains, their presence in healthcare settings and emergence in the community is of growing concern. Protegrin-1 (PG-1) is a broad spectrum antimicrobial peptide effective against bacteria and antibiotic-resistant bacteria. PG-1 may be a potential alternative to conventional antibiotics and its promising therapeutic abilities have been previously demonstrated in infection models and in the reduction of inflammation in chemically-induced murine colitis. In the current study, proform PG-1 (ProPG) was designed to include a novel cleavage site and recombinantly generated for more efficient activation at sites of tissue inflammation. A widely selective matrix metalloproteinase (MMP) cleavage site was inserted into ProPG 5’ to the native neutrophil elastase site to allow for the more efficient release of mature PG-1 at skin inflammation sites where MMPs are abundantly expressed. Pichia pastoris served as the expression host for the constructed expression vector and fermentation parameters were adjusted for optimal ProPG expression and secretion. Cleavage studies of the introduced MMP site performed with recombinant mouse MMP-3, demonstrated the functionality of the inserted MMP-3 site. Future studies will verify the selectivity of the MMP site and the therapeutic potential of ProPG against MRSA infected skin wounds.

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Cancellation, Postponement and Transfer of Registration

All cancellations or modifications of registration must be made in writing to biotechnology@alliedconferences.org

Cancellation Policy

If  Allied Academies cancels this event for any reason, you will receive a credit for 100% of the registration fee paid. You may use this credit for another Allied Academies event which must occur within one year from the date of cancellation.

Postponement

If Allied Academies Ltd postpones an event for any reason and you are unable or unwilling to attend on rescheduled dates, you will receive a credit for 100% of the registration fee paid. You may use this credit for another Allied Academies event which must occur within one year from the date of postponement.

Transfer of registration

All fully paid registrations are transferable to other persons from the same organization, if registered person is unable to attend the event. Transfers must be made by the registered person in writing to biotechnology@alliedconferences.org. Details must be included the full name of replacement person, their title, contact phone number and email address. All other registration details will be assigned to the new person unless otherwise specified.

Registration can be transferred to one conference to another conference of Allied Academies if the person is unable to attend one of conferences.

However, Registration cannot be transferred if it is intimated within 14 days of respective conference.
The transferred registrations will not be eligible for Refund.

Visa Information

Keeping in view of increased security measures, we would like to request all the participants to apply for Visa as soon as possible.

Allied Academies will not directly contact embassies and consulates on behalf of visa applicants. All delegates or invitees should apply for Business Visa only.

Important note for failed visa applications: Visa issues cannot come under the consideration of cancellation policy of Allied Academies, including the inability to obtain a visa.

Refund Policy:

If the registrant is unable to attend, and is not in a position to transfer his/her participation to another person or event, then the following refund arrangements apply:

Keeping in view of advance payments towards Venue, Printing, Shipping, Hotels and other overheads, we had to keep Refund Policy is as following slabs-
  • Before 60 days of the conference: Eligible for Full Refund less $150 service Fee
  • Within 60-46 days of Conference: Eligible for 40% of payment Refund
  • Within 45 days of Conference: Not eligible for Refund

Accommodation Cancellation Policy:

Accommodation Providers (Hotels) have their own cancellation policies, and they generally apply when cancellations are made less than 30 days prior to arrival. Please contact us as soon as possible, if you wish to cancel or amend your accommodation. Allied Academies Ltd will advise the cancellation policy of your accommodation provider, prior to cancelling or amending your booking, to ensure you are fully aware of any non-refundable deposits.


Authorization Policy

Cancellation, Postponement and Transfer of Registration

All cancellations or modifications of registration must be made in writing to biotechnology@alliedconferences.org

Cancellation Policy

If  Allied Academies cancels this event for any reason, you will receive a credit for 100% of the registration fee paid. You may use this credit for another Allied Academies event which must occur within one year from the date of cancellation.

Postponement

If Allied Academies Ltd postpones an event for any reason and you are unable or unwilling to attend on rescheduled dates, you will receive a credit for 100% of the registration fee paid. You may use this credit for another Allied Academies event which must occur within one year from the date of postponement.

Transfer of registration

All fully paid registrations are transferable to other persons from the same organization, if registered person is unable to attend the event. Transfers must be made by the registered person in writing to biotechnology@alliedconferences.org. Details must be included the full name of replacement person, their title, contact phone number and email address. All other registration details will be assigned to the new person unless otherwise specified.

Registration can be transferred to one conference to another conference of Allied Academies if the person is unable to attend one of conferences.

However, Registration cannot be transferred if it is intimated within 14 days of respective conference.
The transferred registrations will not be eligible for Refund.

Visa Information

Keeping in view of increased security measures, we would like to request all the participants to apply for Visa as soon as possible.

Allied Academies will not directly contact embassies and consulates on behalf of visa applicants. All delegates or invitees should apply for Business Visa only.

Important note for failed visa applications: Visa issues cannot come under the consideration of cancellation policy of Allied Academies, including the inability to obtain a visa.

Refund Policy:

If the registrant is unable to attend, and is not in a position to transfer his/her participation to another person or event, then the following refund arrangements apply:

Keeping in view of advance payments towards Venue, Printing, Shipping, Hotels and other overheads, we had to keep Refund Policy is as following slabs-
  • Before 60 days of the conference: Eligible for Full Refund less $150 service Fee
  • Within 60-30 days of Conference: Eligible for 40% of payment Refund
  • Within 45 days of Conference: Not eligible for Refund

Accommodation Cancellation Policy:

Accommodation Providers (Hotels) have their own cancellation policies, and they generally apply when cancellations are made less than 30 days prior to arrival. Please contact us as soon as possible, if you wish to cancel or amend your accommodation. Allied Academies Ltd will advise the cancellation policy of your accommodation provider, prior to cancelling or amending your booking, to ensure you are fully aware of any non-refundable deposits.

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